Special Book Article: Books to Remember

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Book Review | New Books

Background: The need for fast and accurate scoring functions has been driven by the increased use of in silico virtual screening twinned with high-throughput screening as a method to rapidly identify potential candidates in the early stages of drug development. We examine the ability of some the most common scoring functions (GOLD, ChemScore, DOCK, PMF, BLEEP and Consensus) to discriminate corr...

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The neonatal brain, previously so inviolate to imaging techniques other than relatively crude radionuc lide studies , direct contrast ventriculography, and rarely performed angiography or pneumoencephalography by only the most adventuresome or experienced neuroradiolog ists , now has been successfully and safely mastered by computed tomography (CT) and sonography. Widespread interest in and cli...

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This paper reviews the clinical findings in the Hakim-Adams syndrome and distinguishes it from the more general term of normal pressure hydrocephalus. The radiographic tests to diagnose these entities are discussed in their historical context. Computed tomography has recently replaced the pneumoencephalogram for evaluating ventricular size and configuration and computed tomographic metrizamide ...

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The integrative field of developmental psychopathology is having a huge impact on our understanding of human health and behavior. In this paper, I use the example of children’s early stress exposure to illustrate how developmental psychopathologists now tend to deemphasize diagnostic categories and, instead, emphasize the social and biological contexts, events and circumstances that have create...

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Cholesterol is required for fetal development. Data obtained from recent studies in humans, rodents, and cell cultures showed that circulating maternal cholesterol can affect fetal metabolism and sterol accretion. Recent studies in our laboratory showed that the efflux of cholesterol from the basolateral side of the placental cells and the secretion of cholesterol from endodermal yolk sac cells...

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ژورنال

عنوان ژورنال: BioScience

سال: 1997

ISSN: 0006-3568,1525-3244

DOI: 10.2307/1313167